The agreement lays out the rules for how the flights from the state of New Mexico will be integrated into US air space.
In a statement, Virgin Galactic said the deal brings it "another step closer" to commercial space flights.
The agreement with US authorities outlines how the FAA's air traffic control centre in Albuquerque, New Mexico, and the state's Spaceport Authority, will work with Virgin Galactic to make sure there is safe airspace for Virgin Galactic's space plane, the SpaceShipTwo.